Gene
slc38a4
- ID
- ZDB-GENE-041010-14
- Name
- solute carrier family 38 member 4
- Symbol
- slc38a4 Nomenclature History
- Previous Names
-
- wu:fd51c05
- zgc:103694
- zgc:113830
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in liver. Orthologous to human SLC38A4 (solute carrier family 38 member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103694 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la011560Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la028973Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa2147 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa14136 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa20170 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa20171 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa25270 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa31368 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa31369 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013057 | Amino acid transporter, transmembrane domain |
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Domain Details Per Protein
| Protein | Length | Amino acid transporter, transmembrane domain |
|---|---|---|
|
UniProtKB:A0A8M6YZH0
|
538 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc38a4-201
(1)
|
Ensembl | 4,956 nt | ||
| mRNA |
slc38a4-203
(1)
|
Ensembl | 232 nt | ||
| ncRNA |
slc38a4-005
(1)
|
Ensembl | 644 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-132P20 | ZFIN Curated Data | |
| Encodes | EST | fd51c05 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:103694 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:113830 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191264 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192296 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001005944 (1) | 4960 nt | ||
| Genomic | GenBank:AL929171 (1) | 176577 nt | ||
| Polypeptide | UniProtKB:A0A8M6YZH0 (1) | 538 aa |
- Banu, S., Gaur, N., Nair, S., Ravikrishnan, T., Khan, S., Mani, S., Bharathi, S., Mandal, K., Kuram, N.A., Vuppaladadium, S., Ravi, R., Murthy, C.L.N., Quoseena, M., Babu, N.S., Idris, M.M. (2022) Transcriptomic and proteomic analysis of epimorphic regeneration in zebrafish caudal fin tissue. Genomics. 114(2):110300
- Hunter, M.V., Moncada, R., Weiss, J.M., Yanai, I., White, R.M. (2021) Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface. Nature communications. 12:6278
- Wang, X., Zheng, Y., Zhang, Y., Li, J., Zhang, H., Wang, H. (2016) Effects of β-diketone antibiotic mixtures on behavior of zebrafish (Danio rerio). Chemosphere. 144:2195-2205
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Fu, J., Han, J., Zhou, B., Gong, Z., Santos, E.M., Huo, X., Zheng, W., Liu, H., Yu, H., and Liu, C. (2013) Toxicogenomic Responses of Zebrafish Embryos/Larvae to Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) Reveal Possible Molecular Mechanisms of Developmental Toxicity. Environmental science & technology. 47(18):10574-82
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
- Cheng, W., Guo, L., Zhang, Z., Soo, H.M., Wen, C., Wu, W., and Peng, J. (2006) HNF factors form a network to regulate liver-enriched genes in zebrafish. Developmental Biology. 294(2):482-496
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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