Gene
csrp3
- ID
- ZDB-GENE-041010-119
- Name
- cysteine and glycine-rich protein 3 (cardiac LIM protein)
- Symbol
- csrp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have actinin binding activity. Involved in heart contraction and sarcomere organization. Predicted to localize to Z disc and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Is expressed in musculature system; pericardial region; and trunk. Orthologous to human CSRP3 (cysteine and glycine rich protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1M | Alliance | ?Cardiomyopathy, dilated, 1M | 607482 |
| hypertrophic cardiomyopathy 12 | Alliance | Cardiomyopathy, hypertrophic, 12 | 612124 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001781 | Zinc finger, LIM-type |
Domain Details Per Protein
| Protein | Length | Zinc finger, LIM-type |
|---|---|---|
|
UniProtKB:A0A8M1P2D0
|
222 | |
|
UniProtKB:F1QJC0
|
193 |
Interactions and Pathways
No data available
Plasmids
No data available