ZFIN is now using GRCz12tu for Genomic Data
Gene
polr2b
- ID
- ZDB-GENE-041008-1
- Name
- RNA polymerase II subunit B
- Symbol
- polr2b Nomenclature History
- Previous Names
-
- zgc:109952
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including nucleotidyltransferase activity; ribonucleoside binding activity; and zinc ion binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in DNA-templated transcription elongation and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II, core complex. Orthologous to human POLR2B (RNA polymerase II subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109952 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR007121 | RNA polymerase, beta subunit, conserved site |
| Domain | IPR007120 | DNA-directed RNA polymerase, subunit 2, hybrid-binding domain |
| Domain | IPR007641 | RNA polymerase Rpb2, domain 7 |
| Domain | IPR007642 | RNA polymerase Rpb2, domain 2 |
| Domain | IPR007644 | RNA polymerase, beta subunit, protrusion |
| Domain | IPR007645 | RNA polymerase Rpb2, domain 3 |
| Domain | IPR007646 | RNA polymerase Rpb2, domain 4 |
| Domain | IPR007647 | RNA polymerase Rpb2, domain 5 |
| Family | IPR015712 | DNA-directed RNA polymerase, subunit 2 |
| Homologous_superfamily | IPR014724 | RNA polymerase Rpb2, OB-fold |
| Homologous_superfamily | IPR037033 | DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily |
| Homologous_superfamily | IPR037034 | RNA polymerase Rpb2, domain 2 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DNA-directed RNA polymerase, subunit 2 | DNA-directed RNA polymerase, subunit 2, hybrid-binding domain | DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily | RNA polymerase, beta subunit, conserved site | RNA polymerase, beta subunit, protrusion | RNA polymerase Rpb2, domain 2 | RNA polymerase Rpb2, domain 2 superfamily | RNA polymerase Rpb2, domain 3 | RNA polymerase Rpb2, domain 4 | RNA polymerase Rpb2, domain 5 | RNA polymerase Rpb2, domain 7 | RNA polymerase Rpb2, OB-fold |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1N6S0 | InterPro | 1174 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
polr2b-202
(1)
|
Ensembl | 1,345 nt | ||
| mRNA |
polr2b-203
(1)
|
Ensembl | 1,764 nt | ||
| mRNA |
polr2b-204
(1)
|
Ensembl | 6,508 nt | ||
| ncRNA |
polr2b-003
(1)
|
Ensembl | 360 nt | ||
| ncRNA |
polr2b-004
(1)
|
Ensembl | 823 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers