Gene
prkchb
- ID
- ZDB-GENE-041001-104
- Name
- protein kinase C, eta, b
- Symbol
- prkchb Nomenclature History
- Previous Names
-
- prkch
- si:ch211-212g7.5
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in cerebral infarction. Orthologous to human PRKCH (protein kinase C eta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cerebral infarction | Alliance | {Cerebral infarction, susceptibility to} | 601367 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000008 | C2 domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR017892 | Protein kinase, C-terminal |
| Domain | IPR020454 | Diacylglycerol/phorbol-ester binding |
| Domain | IPR034665 | Novel protein kinase C eta, catalytic domain |
| Family | IPR014376 | Protein kinase C, delta/epsilon/eta/theta types |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | C1-like domain superfamily | C2 domain | C2 domain superfamily | Diacylglycerol/phorbol-ester binding | Novel protein kinase C eta, catalytic domain | Protein kinase, ATP binding site | Protein kinase C, delta/epsilon/eta/theta types | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5TZD4
|
676 | |||||||||||||
|
UniProtKB:A0A2R8Q5P7
|
676 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prkchb-201
(1)
|
Ensembl | 2,198 nt | ||
| mRNA |
prkchb-202
(1)
|
Ensembl | 5,647 nt | ||
| mRNA |
prkchb-203
(1)
|
Ensembl | 5,725 nt | ||
| mRNA |
prkchb-204
(1)
|
Ensembl | 5,324 nt |
Interactions and Pathways
No data available
Plasmids
No data available