Gene
mast3a
- ID
- ZDB-GENE-040914-35
- Name
- microtubule associated serine/threonine kinase 3a
- Symbol
- mast3a Nomenclature History
- Previous Names
-
- mast3
- im:6911368
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization; intracellular signal transduction; and protein phosphorylation. Orthologous to human MAST3 (microtubule associated serine/threonine kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6911368 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shu et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
developmental and epileptic encephalopathy 108 | Alliance | Developmental and epileptic encephalopathy 108 | 620115 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR000961 | AGC-kinase, C-terminal |
Domain | IPR001478 | PDZ domain |
Domain | IPR015022 | Microtubule-associated serine/threonine-protein kinase, pre-PK domain |
Domain | IPR037711 | Microtubule-associated serine/threonine-protein kinase, catalytic domain |
Domain | IPR041489 | PDZ domain 6 |
Family | IPR050236 | Serine/threonine-protein kinases, AGC |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR023142 | Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily |
Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
Protein | Length | AGC-kinase, C-terminal | Microtubule-associated serine/threonine-protein kinase, catalytic domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain | Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily | PDZ domain | PDZ domain 6 | PDZ superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine/threonine-protein kinases, AGC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QZB3
|
1295 | |||||||||||
UniProtKB:A0A8M9PPY9
|
1355 | |||||||||||
UniProtKB:A0A8M9PXC1
|
1351 | |||||||||||
UniProtKB:A0A8M9Q0N6
|
1354 | |||||||||||
UniProtKB:A0A8M9PSZ3
|
1318 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance