Gene
sf3b1
- ID
- ZDB-GENE-040827-3
- Name
- splicing factor 3b, subunit 1
- Symbol
- sf3b1 Nomenclature History
- Previous Names
-
- tst
- wu:fb99f09
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity. Involved in several processes, including hemopoiesis; melanocyte differentiation; and neural crest cell development. Predicted to localize to U2 snRNP and spliceosomal complex. Human ortholog(s) of this gene implicated in myelodysplastic syndrome. Is expressed in brain; neural tube; and trunk. Orthologous to human SF3B1 (splicing factor 3b subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145777 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myelodysplastic syndrome | Alliance | Myelodysplastic syndrome, somatic | 614286 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Splicing factor 3B subunit 1 | Splicing factor 3B subunit 1-like |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B2S8
|
160 | ||||
|
UniProtKB:F1QQZ1
|
1315 | ||||
|
UniProtKB:A0A8M2BF86
|
1161 | ||||
|
UniProtKB:A0A8M3AW70
|
146 | ||||
|
UniProtKB:A0A8M2BF81
|
1272 |
Interactions and Pathways
No data available
Plasmids
No data available