Gene
nomo
- ID
- ZDB-GENE-040826-3
- Name
- nodal modulator
- Symbol
- nomo Nomenclature History
- Previous Names
-
- loc283820
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable carbohydrate binding activity. Involved in cartilage development; determination of left/right asymmetry in lateral mesoderm; and negative regulation of nodal signaling pathway. Acts upstream of or within adult locomotory behavior; regulation of signal transduction; and social behavior. Located in endoplasmic reticulum membrane. Is expressed in several structures, including heart; liver; mesoderm; nervous system; and pleuroperitoneal region. Used to study autistic disorder.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| autistic disorder | nomozf3952/zf3952 | standard conditions | Zhang et al., 2024 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Carbohydrate-binding-like fold | ER membrane protein complex subunit 7, beta-sandwich domain | Serine-Aspartate Repeat-Containing |
|---|---|---|---|---|---|
| UniProtKB:X1WEJ6 | InterPro | 1208 |
Interactions and Pathways
No data available
Plasmids
No data available