Gene

htra3a

ID

ZDB-GENE-040801-245

Name

HtrA serine peptidase 3a

Symbol

htra3a Nomenclature History

Previous Names

zgc:91963 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have insulin-like growth factor binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular region. Orthologous to human HTRA3 (HtrA serine peptidase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91963 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With htra3a Human Ortholog

No data available

Associated With htra3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Domain	IPR001478	PDZ domain
Domain	IPR002350	Kazal domain
Domain	IPR041489	PDZ domain 6
Family	IPR001940	Peptidase S1C
Homologous_superfamily	IPR009003	Peptidase S1, PA clan
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036058	Kazal domain superfamily

Domain Details Per Protein

Protein	Length	Growth factor receptor cysteine-rich domain superfamily	Insulin-like growth factor-binding protein, IGFBP	Kazal domain	Kazal domain superfamily	PDZ domain	PDZ domain 6	PDZ superfamily	Peptidase S1C	Peptidase S1, PA clan
UniProtKB:Q6DBR1 InterPro	489

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	htra3a-201 (1) Ensembl	Ensembl	3,269 nt	Select Tool ZFIN BLAST
mRNA	htra3a-202 (1) Ensembl	Ensembl	663 nt	Select Tool
mRNA	htra3a-203 (1) Ensembl	Ensembl	2,050 nt	Select Tool ZFIN BLAST
mRNA	htra3a-204 (1) Ensembl	Ensembl	3,269 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations