Gene
rab18b
- ID
- ZDB-GENE-040801-185
- Name
- RAB18B, member RAS oncogene family
- Symbol
- rab18b Nomenclature History
- Previous Names
-
- zgc:92523
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity. Involved in brain development and eye development. Acts upstream of or within chordate embryonic development. Predicted to be located in lipid droplet. Predicted to be active in Golgi apparatus. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bem et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bem et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Warburg micro syndrome 3 | Alliance | Warburg micro syndrome 3 | 614222 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rab | Sigma-54 interaction domain, ATP-binding site 1 | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6DHC1
|
205 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rab18b-201
(1)
|
Ensembl | 1,805 nt |
Interactions and Pathways
No data available
Plasmids