Gene
ndufa7
- ID
- ZDB-GENE-040801-169
- Name
- NADH:ubiquinone oxidoreductase subunit A7
- Symbol
- ndufa7 Nomenclature History
- Previous Names
-
- zgc:92850
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Acts upstream of or within heart development and regulation of calcineurin-mediated signaling. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; eye; immature eye; midbrain; and pectoral fin musculature. Used to study hypertrophic cardiomyopathy. Orthologous to human NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92850 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Shi et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hypertrophic cardiomyopathy | twu34Tg + MO1-ndufa7 | standard conditions | Shi et al., 2020 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009947 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 |
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 |
|---|---|---|
|
UniProtKB:Q6DGM9
|
104 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufa7-201
(1)
|
Ensembl | 482 nt |
Interactions and Pathways
No data available
Plasmids
No data available