Gene
ptpa
- ID
- ZDB-GENE-040801-11
- Name
- protein phosphatase 2 phosphatase activator
- Symbol
- ptpa Nomenclature History
- Previous Names
-
- fc23d07
- ppp2r4 (1)
- wu:fc23d07
- zgc:92766
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable peptidyl-prolyl cis-trans isomerase activity and protein tyrosine phosphatase activator activity. Predicted to be involved in mitotic spindle organization. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTPA (protein phosphatase 2 phosphatase activator).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6908074 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinson's disease 25 | Alliance | Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development | 620482 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phosphotyrosyl phosphatase activator, C-terminal lid domain | Phosphotyrosyl phosphatase activator, PTPA | PTPA superfamily |
|---|---|---|---|---|
|
UniProtKB:A2CF49
|
324 |
Interactions and Pathways
No data available
Plasmids
No data available