ZFIN ID: ZDB-GENE-040724-44
Gene Name: euchromatic histone-lysine N-methyltransferase 1a
Gene Symbol: ehmt1a
Previous Names: si:rp71-1o1.6, zgc:136244
Location: Chr: 5   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7154822]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la024948Tg, sa18521
Knockdown reagents: MO1-ehmt1a (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Kleefstra syndrome 610253
GENE ONTOLOGY
Ontology GO Term
Biological Process histone lysine methylation (more)
Cellular Component chromosome (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR002110 (1)
  • InterPro:IPR007728 (1)
  • InterPro:IPR020683 (1)
  • PROSITE:PS50088 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50297 (1)
  • PROSITE:PS50867 (1)
  • Pfam:PF00856 (1)
  • Pfam:PF05033 (1)
  • Pfam:PF12796 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ehmt1a-001 (1) 3795
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ehmt1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ehmt1a Contained in: [BAC] DKEY-225K7 (1), RP71-1O1 (order this)
    ehmt1a Encodes: [EST] IMAGE:7154822 (1) (order this)
    [cDNA] MGC:136244 (1) (order this), MGC:198408 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030131 (1) 3177 bp
    Genomic GenBank:AL831768 (1) 149457 bp
    Select Tool
    Polypeptide UniProtKB:B7ZVR6 (1) 1059 aa
    Sequence Clusters UniGene:83090 (1)
    Sequence Information (all 34)
    OTHER ehmt1a GENE PAGES
  • Gene:100005761 (1)
  • VEGA:OTTDARG00000002168 (1)
  • Ensembl(Zv9):ENSDARG00000068157 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ehmt1a 5  
    Human EHMT1 9 (9q34.3)
  • OMIM:607001
  • Gene:79813
  • Mouse Ehmt1 2 ( 16.73 cM)
  • MGI:1924933
  • Gene:77683
  • Orthology Details
    CITATIONS (22)