Gene
slc25a23b
- ID
- ZDB-GENE-040724-220
- Name
- solute carrier family 25 member 23b
- Symbol
- slc25a23b Nomenclature History
- Previous Names
-
- slc25a41
- si:dkey-204f11.59 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable ATP transmembrane transporter activity. Predicted to be involved in ADP transport and ATP transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to several human genes including SLC25A23 (solute carrier family 25 member 23).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR002067 | Mitochondrial carrier protein |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR023395 | Mitochondrial carrier domain superfamily |
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Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial substrate/solute carrier |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5PNM8
|
481 | ||||||
|
UniProtKB:A0A8M9PHW1
|
306 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc25a23b-201
(1)
|
Ensembl | 1,446 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204F11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001044952 (1) | 1446 nt | ||
| Genomic | GenBank:BX649502 (1) | 247387 nt | ||
| Polypeptide | UniProtKB:Q5PNM8 (1) | 481 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | SLC25A23 | 19 | Amino acid sequence comparison (1) Conserved genome location (synteny) (1) | |
| Human | SLC25A41 | 19 | Amino acid sequence comparison (1) Conserved genome location (synteny) (1) | |
| Mouse | Slc25a23 | 17 | Amino acid sequence comparison (1) Conserved genome location (synteny) (1) | |
| Mouse | Slc25a41 | 17 | Conserved genome location (synteny) (1) Amino acid sequence comparison (1) |
- Hofherr, A., Seger, C., Fitzpatrick, F., Busch, T., Michel, E., Luan, J., Osterried, L., Linden, F., Kramer-Zucker, A., Wakimoto, B., Schütze, C., Wiedemann, N., Artati, A., Adamski, J., Walz, G., Kunji, E.R.S., Montell, C., Watnick, T., Köttgen, M. (2018) The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. PLoS Biology. 16:e2005651
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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