Gene
nek6
- ID
- ZDB-GENE-040724-133
- Name
- NIMA-related kinase 6
- Symbol
- nek6 Nomenclature History
- Previous Names
-
- si:ch211-167p9.4
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromosome segregation; peptidyl-serine phosphorylation; and regulation of mitotic metaphase/anaphase transition. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of proteasome complex. Predicted to be active in cytosol. Orthologous to human NEK6 (NIMA related kinase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Guo et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001584 | Integrase, catalytic core |
| Domain | IPR001878 | Zinc finger, CCHC-type |
| Domain | IPR040676 | Domain of unknown function DUF5641 |
| Family | IPR005312 | Protein of unknown function DUF1759 |
| Family | IPR008042 | Retrotransposon, Pao |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Length | DNA/RNA polymerase superfamily | Domain of unknown function DUF5641 | Integrase, catalytic core | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Protein of unknown function DUF1759 | Retrotransposon, Pao | Ribonuclease H-like superfamily | Ribonuclease H superfamily | Serine/threonine-protein kinase, active site | Serine-threonine/tyrosine-protein kinase, catalytic domain | Zinc finger, CCHC-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1RFQ9
|
309 | |||||||||||||
|
UniProtKB:A0A8M6YUQ1
|
1996 | |||||||||||||
|
UniProtKB:A0A8M9PUE6
|
299 |
Interactions and Pathways
No data available
Plasmids
No data available