Gene
ctdp1
- ID
- ZDB-GENE-040720-1
- Name
- CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
- Symbol
- ctdp1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be located in nucleus. Orthologous to human CTDP1 (CTD phosphatase subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| hi998Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa23473 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa23474 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa32238 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa36797 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa43245 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital cataracts, facial dysmorphism, and neuropathy | 604168 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | CTD phosphatase Fcp1 | FCP1 homology domain | FCP1-like phosphatase, C-terminal | FCP1-like phosphatase, phosphatase domain | HAD-like superfamily | HAD superfamily | Single hybrid motif |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DRN5
|
947 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-139E14 | ZFIN Curated Data | |
| Contained in | BAC | CH211-169C1 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-261N3 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002873 (1) | 2868 nt | ||
| Genomic | GenBank:CR548625 (2) | 195124 nt | ||
| Polypeptide | UniProtKB:Q6DRN5 (1) | 947 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
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