Gene
aldh3a2a
- ID
- ZDB-GENE-040718-74
- Name
- aldehyde dehydrogenase 3 family, member A2a
- Symbol
- aldh3a2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have 3-chloroallyl aldehyde dehydrogenase activity. Predicted to be involved in cellular aldehyde metabolic process and oxidation-reduction process. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Sjogren-Larsson syndrome and arteriosclerosis. Orthologous to human ALDH3A1 (aldehyde dehydrogenase 3 family member A1) and ALDH3A2 (aldehyde dehydrogenase 3 family member A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92064 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sjogren-Larsson syndrome | Alliance | Sjogren-Larsson syndrome | 270200 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR016160 | Aldehyde dehydrogenase, cysteine active site |
| Conserved_site | IPR029510 | Aldehyde dehydrogenase, glutamic acid active site |
| Domain | IPR015590 | Aldehyde dehydrogenase domain |
| Family | IPR012394 | Aldehyde dehydrogenase NAD(P)-dependent |
| Homologous_superfamily | IPR016161 | Aldehyde/histidinol dehydrogenase |
| Homologous_superfamily | IPR016162 | Aldehyde dehydrogenase, N-terminal |
| Homologous_superfamily | IPR016163 | Aldehyde dehydrogenase, C-terminal |
Domain Details Per Protein
| Protein | Length | Aldehyde dehydrogenase, C-terminal | Aldehyde dehydrogenase, cysteine active site | Aldehyde dehydrogenase domain | Aldehyde dehydrogenase, glutamic acid active site | Aldehyde dehydrogenase NAD(P)-dependent | Aldehyde dehydrogenase, N-terminal | Aldehyde/histidinol dehydrogenase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q90ZZ8
|
488 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
aldh3a2a-201
(1)
|
Ensembl | 2,072 nt | ||
| mRNA |
aldh3a2a-202
(1)
|
Ensembl | 462 nt | ||
| mRNA |
aldh3a2a-204
(1)
|
Ensembl | 664 nt | ||
| mRNA |
aldh3a2a-205
(1)
|
Ensembl | 2,657 nt | ||
| mRNA |
aldh3a2a-206
(1)
|
Ensembl | 4,218 nt | ||
| mRNA |
aldh3a2a-207
(1)
|
Ensembl | 2,886 nt | ||
| ncRNA |
aldh3a2a-004
(1)
|
Ensembl | 797 nt |
Interactions and Pathways
No data available
Plasmids
No data available