Gene

nelfe

ID
ZDB-GENE-040718-69
Name
negative elongation factor complex member E
Symbol
nelfe Nomenclature History
Previous Names
  • rdbp
  • zgc:92496
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Involved in positive regulation of hematopoietic stem cell differentiation. Predicted to localize to NELF complex. Orthologous to human NELFE (negative elongation factor complex member E).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa13558Allele with one point mutationUnknownSplice SiteENU
sa29220Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-nelfeN/A (2)
MO2-nelfeN/AYang et al., 2016
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Human Disease
Associated With nelfe Human Ortholog
No data available
Associated With nelfe Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034637 Negative elongation factor E, RNA recognition motif
Family IPR033102 Negative elongation factor E
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
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Domain Details Per Protein
Protein Length Negative elongation factor E Negative elongation factor E, RNA recognition motif Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A0A8M9PN91 378
UniProtKB:Q1LWQ2 346
UniProtKB:Q6DHD7 346
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 19
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript nelfe-202 (1) Ensembl 322 nt
mRNA nelfe-201 (1) Ensembl 1,202 nt
mRNA nelfe-203 (1) Ensembl 1,638 nt
mRNA nelfe-204 (1) Ensembl 779 nt
mRNA nelfe-205 (1) Ensembl 3,119 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-276C21ZFIN Curated Data
Contained inBACCH211-222E23ZFIN Curated Data
EncodescDNAMGC:92496ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNELFE6
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseNelfe17
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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