Gene
ica1
- ID
- ZDB-GENE-040718-490
- Name
- islet cell autoantigen 1
- Symbol
- ica1 Nomenclature History
- Previous Names
-
- zgc:92566 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have protein domain specific binding activity. Predicted to be involved in regulation of insulin secretion. Predicted to localize to Golgi membrane and secretory granule membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in central nervous system; neurons; rhombomere; and ventricular zone. Orthologous to human ICA1 (islet cell autoantigen 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92566 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | Arfaptin homology (AH) domain | Islet cell autoantigen 1/Ica1-like | Islet cell autoantigen Ica1, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:E7EXU4
|
|||||
|
UniProtKB:Q6DHA0
|
449 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance