Gene
cldn11a
- ID
- ZDB-GENE-040718-369
- Name
- claudin 11a
- Symbol
- cldn11a Nomenclature History
- Previous Names
-
- zgc:92247
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in cell junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in brain; cardiovascular system; gill; integument; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human CLDN11 (claudin 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypomyelinating leukodystrophy 22 | Alliance | Leukodystrophy, hypomyelinating, 22 | 619328 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin-11 | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|---|
|
UniProtKB:Q6DHL0
|
215 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cldn11a-201
(1)
|
Ensembl | 1,316 nt |
Interactions and Pathways
No data available
Plasmids
No data available