Gene
rxrgb
- ID
- ZDB-GENE-040718-34
- Name
- retinoid X receptor, gamma b
- Symbol
- rxrgb Nomenclature History
- Previous Names
-
- nr2b3b (1)
- zgc:92183
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have nuclear receptor activity and retinoic acid-responsive element binding activity. Predicted to be involved in several processes, including positive regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to localize to RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is expressed in several structures, including Kupffer's vesicle; liver; neural rod; paraxial mesoderm; and retina. Orthologous to human RXRG (retinoid X receptor gamma).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- bc075918 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Domain | IPR021780 | Nuclear/hormone receptor activator site AF-1 |
| Family | IPR000003 | Retinoid X receptor/HNF4 |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050274 | Nuclear hormone receptor family NR2 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear/hormone receptor activator site AF-1 | Nuclear hormone receptor family NR2 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Retinoid X receptor/HNF4 | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B7K1
|
465 | ||||||||
|
UniProtKB:Q6DHP9
|
452 |
Interactions and Pathways
No data available
Plasmids
No data available