Gene

vamp1b

ID
ZDB-GENE-040718-265
Name
vesicle associated membrane protein 1b
Symbol
vamp1b Nomenclature History
Previous Names
  • zgc:92912
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have SNAP receptor activity and syntaxin binding activity. Predicted to be involved in SNARE complex assembly. Predicted to localize to SNARE complex and plasma membrane. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Is expressed in hindbrain; midbrain; neurons; retina; and spinal cord. Orthologous to human VAMP1 (vesicle associated membrane protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vamp1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spastic ataxia 1 Alliance Spastic ataxia 1, autosomal dominant 108600
Myasthenic syndrome, congenital, 25 618323
Associated With vamp1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR042855 v-SNARE, coiled-coil homology domain
Family IPR001388 Synaptobrevin-like
Family IPR016444 Synaptobrevin/Vesicle-associated membrane protein
Domain Details Per Protein
Protein Length Synaptobrevin-like Synaptobrevin/Vesicle-associated membrane protein v-SNARE, coiled-coil homology domain
UniProtKB:Q6DGI1 118
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations