Gene

mapkapk5

ID
ZDB-GENE-040718-25
Name
MAPK activated protein kinase 5
Symbol
mapkapk5 Nomenclature History
Previous Names
  • zgc:92197
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have calmodulin binding activity; mitogen-activated protein kinase binding activity; and protein serine/threonine kinase activity. Predicted to be involved in Ras protein signal transduction; negative regulation of TOR signaling; and protein phosphorylation. Predicted to localize to cytoplasm and nucleus. Orthologous to human MAPKAPK5 (MAPK activated protein kinase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Nguyen et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mapkapk5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurocardiofaciodigital syndrome 619869
Associated With mapkapk5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Family IPR050205 Calcium-dependent Serine/Threonine Protein Kinases
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR027442 MAP kinase activated protein kinase, C-terminal
Domain Details Per Protein
Protein Length Calcium-dependent Serine/Threonine Protein Kinases MAP kinase activated protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q6DHN7 471
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mapkapk5-201 (1) Ensembl 2,232 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations