Gene
mapkapk5
- ID
- ZDB-GENE-040718-25
- Name
- MAPK activated protein kinase 5
- Symbol
- mapkapk5 Nomenclature History
- Previous Names
-
- zgc:92197
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity; mitogen-activated protein kinase binding activity; and protein serine/threonine kinase activity. Predicted to be involved in Ras protein signal transduction; negative regulation of TOR signaling; and protein phosphorylation. Predicted to localize to cytoplasm and nucleus. Orthologous to human MAPKAPK5 (MAPK activated protein kinase 5).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Nguyen et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurocardiofaciodigital syndrome | 619869 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
Domain | IPR000719 | Protein kinase domain |
Family | IPR050205 | Calcium-dependent Serine/Threonine Protein Kinases |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR027442 | MAP kinase activated protein kinase, C-terminal |
Domain Details Per Protein
Protein | Length | Calcium-dependent Serine/Threonine Protein Kinases | MAP kinase activated protein kinase, C-terminal | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
---|---|---|---|---|---|---|
UniProtKB:Q6DHN7
|
471 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
mapkapk5-201
(1)
|
Ensembl | 2,232 nt |
Interactions and Pathways
No data available
Plasmids
No data available