Gene
impa1
- ID
- ZDB-GENE-040718-245
- Name
- inositol monophosphatase 1
- Symbol
- impa1 Nomenclature History
- Previous Names
-
- zgc:100926
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process; inositol phosphate dephosphorylation; and signal transduction. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human IMPA1 (inositol monophosphatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145589 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 59 | Alliance | Intellectual developmental disorder, autosomal recessive 59 | 617323 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR020583 | Inositol monophosphatase, metal-binding site |
| Conserved_site | IPR020550 | Inositol monophosphatase, conserved site |
| Family | IPR000760 | Inositol monophosphatase-like |
| Family | IPR020552 | Inositol monophosphatase, lithium-sensitive |
| Family | IPR033942 | Inositol monophosphatase |
Domain Details Per Protein
| Protein | Length | Inositol monophosphatase | Inositol monophosphatase, conserved site | Inositol monophosphatase-like | Inositol monophosphatase, lithium-sensitive | Inositol monophosphatase, metal-binding site |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6DGB2
|
282 |
Interactions and Pathways
No data available
Plasmids
No data available