Gene
sypb
- ID
- ZDB-GENE-040718-205
- Name
- synaptophysin b
- Symbol
- sypb Nomenclature History
- Previous Names
-
- zgc:136469
- zgc:92837
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have syntaxin-1 binding activity. Predicted to be involved in regulation of neuronal synaptic plasticity. Predicted to localize to presynaptic active zone and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Is expressed in central nervous system; lateral wall spinal cord; midbrain; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human SYP (synaptophysin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 96 | Alliance | Intellectual developmental disorder, X-linked 96 | 300802 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Marvel domain | Synaptophysin/synaptoporin |
|---|---|---|---|
|
UniProtKB:B0S6H6
|
297 |
Interactions and Pathways
No data available
Plasmids