Gene

brap

ID

ZDB-GENE-040718-168

Name

BRCA1 associated protein

Symbol

brap Nomenclature History

Previous Names

zgc:92894

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Ras protein signal transduction and protein ubiquitination. Predicted to be active in cytoplasm. Is expressed in lens. Orthologous to human BRAP (BRCA1 associated protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6892431 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With brap Human Ortholog

No data available

Associated With brap Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001607	Zinc finger, UBP-type
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR011422	BRCA1-associated 2/ETP1, RRM
Domain	IPR034932	BRAP2, RNA recognition motif
Domain	IPR047243	BRCA1-associated protein, RING finger, H2 subclass
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR035979	RNA-binding domain superfamily