Gene

gapvd1

ID

ZDB-GENE-040718-117

Name

GTPase activating protein and VPS9 domains 1

Symbol

gapvd1 Nomenclature History

Previous Names

zgc:92666

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to act upstream of or within endocytosis. Predicted to be located in membrane. Predicted to be active in cytosol and endocytic vesicle. Orthologous to human GAPVD1 (GTPase activating protein and VPS9 domains 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gapvd1 Human Ortholog

No data available

Associated With gapvd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001936	Ras GTPase-activating domain
Domain	IPR003123	VPS9 domain
Domain	IPR041545	RABX5, catalytic core helical domain
Family	IPR045046	Vacuolar protein sorting-associated protein 9-like
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR037191	VPS9 domain superfamily

Domain Details Per Protein

Protein	Length	RABX5, catalytic core helical domain	Ras GTPase-activating domain	Rho GTPase activation protein	Vacuolar protein sorting-associated protein 9-like	VPS9 domain	VPS9 domain superfamily
UniProtKB:A0A8M3AVA8 InterPro	1456
UniProtKB:A0A8M3B237 InterPro	1484
UniProtKB:A0A8M3BBW9 InterPro	1457
UniProtKB:A0A8M3AVB1 InterPro	1483
UniProtKB:E7F237 InterPro	1445
UniProtKB:A0A2R8Q516 InterPro	1473

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gapvd1-201 (1) Ensembl	Ensembl	5,128 nt	Select Tool ZFIN BLAST
mRNA	gapvd1-202 (1) Ensembl	Ensembl	1,789 nt	Select Tool ZFIN BLAST
mRNA	gapvd1-203 (1) Ensembl	Ensembl	5,067 nt	Select Tool ZFIN BLAST
mRNA	gapvd1-204 (1) Ensembl	Ensembl	4,442 nt	Select Tool ZFIN BLAST
mRNA	gapvd1-205 (1) Ensembl	Ensembl	4,289 nt	Select Tool ZFIN BLAST
mRNA	gapvd1-206 (1) Ensembl	Ensembl	4,283 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations