Gene

sgtb

ID

ZDB-GENE-040704-72

Name

small glutamine rich tetratricopeptide repeat co-chaperone beta

Symbol

sgtb Nomenclature History

Previous Names

sgta
zgc:92462

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have molecular adaptor activity. Predicted to be involved in positive regulation of chaperone-mediated protein folding; posttranslational protein targeting to endoplasmic reticulum membrane; and ubiquitin-dependent ERAD pathway. Predicted to localize to TRC complex and membrane. Orthologous to human SGTB (small glutamine rich tetratricopeptide repeat containing beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92462 (1 image)
IMAGE:7162654 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sgtb Human Ortholog

No data available

Associated With sgtb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032374	SGTA, homodimerisation domain
Family	IPR047150	SGT
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR013105	Tetratricopeptide repeat 2
Repeat	IPR019734	Tetratricopeptide repeat