Gene
nr4a1
- ID
- ZDB-GENE-040704-11
- Name
- nuclear receptor subfamily 4, group A, member 1
- Symbol
- nr4a1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear glucocorticoid receptor binding activity. Acts upstream of or within regulation of glucose metabolic process. Predicted to be located in cytosol. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in axis; myotome; nervous system; and pectoral fin. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92434 (9 images)
- IMAGE:7162027 (1 image)
- bc074092 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Xu et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003070 | Nuclear receptor subfamily 4 group A member 1-3 |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Nuclear receptor subfamily 4 group A member 1-3 | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6GMG3
|
574 |
Interactions and Pathways
Plasmids
No data available