Gene
rab1bb
- ID
- ZDB-GENE-040625-133
- Name
- RAB1B, member RAS oncogene family b
- Symbol
- rab1bb Nomenclature History
- Previous Names
-
- wu:fc83b07
- zgc:86773
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be active in endomembrane system. Is expressed in central nervous system. Orthologous to several human genes including RAB1B (RAB1B, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6906477 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa991 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa16382 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa24876 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa27623 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rab | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q4V984
|
201 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rab1bb-201
(1)
|
Ensembl | 1,333 nt | ||
| mRNA |
rab1bb-202
(1)
|
Ensembl | 1,865 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-48M5 | ZFIN Curated Data | |
| Encodes | EST | fc83b07 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:6906477 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:86773 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:113919 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001002129 (1) | 2029 nt | ||
| Genomic | GenBank:BX005027 (1) | 241472 nt | ||
| Polypeptide | UniProtKB:Q4V984 (1) | 201 aa |
- Nikolaou, N., Gordon, P.M., Hamid, F., Taylor, R., Lloyd-Jones, J., Makeyev, E.V., Houart, C. (2022) Cytoplasmic pool of U1 spliceosome protein SNRNP70 shapes the axonal transcriptome and regulates motor connectivity. Current biology : CB. 32(23):5099-5115.e8
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Hall, T.E., Martel, N., Lo, H.P., Xiong, Z., Parton, R.G. (2017) A plasmid library of full-length zebrafish rab proteins for in vivo cell biology.. Cellular logistics. 7:e1301151
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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