Gene

otud6b

ID

ZDB-GENE-040426-974

Name

OTU deubiquitinase 6B

Symbol

otud6b Nomenclature History

Previous Names

zgc:56305

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have thiol-dependent ubiquitin-specific protease activity. Predicted to be involved in protein deubiquitination. Orthologous to several human genes including OTUD6B (OTU deubiquitinase 6B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7165283 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Zhou et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With otud6b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder with dysmorphic facies, seizures, and distal limb anomalies	617452

Associated With otud6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003323	OTU domain
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	OTU domain	Papain-like cysteine peptidase superfamily
UniProtKB:Q7ZV00 InterPro	293

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	otud6b-202 (1) Ensembl	Havana	1359 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	otud6b-002 (1) Ensembl	Havana	854 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations