Gene
cox15
- ID
- ZDB-GENE-040426-955
- Name
- cytochrome c oxidase assembly homolog 15 (yeast)
- Symbol
- cox15 Nomenclature History
- Previous Names
-
- wu:fa18g06
- zgc:56240
- zgc:77422
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process. Predicted to act upstream of or within heme biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; hypertrophic cardiomyopathy; and mitochondrial complex IV deficiency nuclear type 6. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 6 | Alliance | Mitochondrial complex IV deficiency, nuclear type 6 | 615119 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | COX15/CtaA family | Heme A synthase, type 2 | Peptidase S1, PA clan |
|---|---|---|---|---|---|
| UniProtKB:F1R355 | InterPro | 399 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available