Gene

clec16a

ID

ZDB-GENE-040426-951

Name

C-type lectin domain containing 16A

Symbol

clec16a Nomenclature History

Previous Names

zgc:56230

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have Rab GTPase binding activity. Predicted to be involved in endosomal transport; endosome to lysosome transport; and regulation of autophagosome maturation. Predicted to colocalize with late endosome. Human ortholog(s) of this gene implicated in Addison's disease; multiple sclerosis; rheumatoid arthritis; and type 1 diabetes mellitus. Orthologous to human CLEC16A (C-type lectin domain containing 16A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56230 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Smits et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With clec16a Human Ortholog

No data available

Associated With clec16a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR019155	CLEC16A/TT9, N-terminal
Domain	IPR045820	CLEC16A/TT9, C-terminal
Family	IPR039272	CLEC16A/TT9

Domain Details Per Protein

Protein	Length	CLEC16A/TT9	CLEC16A/TT9, C-terminal	CLEC16A/TT9, N-terminal
UniProtKB:A0A8M2BB67 InterPro	1028
UniProtKB:A0A8M2BB38 InterPro	1030
UniProtKB:A0A8M1RNA6 InterPro	1046
UniProtKB:A0A8M9PR56 InterPro	932
UniProtKB:A0A8M2BBF3 InterPro	1044