Gene
fxr2
- ID
- ZDB-GENE-040426-943
- Name
- FMR1 autosomal homolog 2
- Symbol
- fxr2 Nomenclature History
- Previous Names
-
- id:ibd5046
- zgc:56215
- zgc:77472
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable mRNA 3'-UTR binding activity; protein homodimerization activity; and translation regulator activity. Predicted to be involved in several processes, including post-transcriptional regulation of gene expression; regulation of alternative mRNA splicing, via spliceosome; and regulation of filopodium assembly. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytoplasm. Predicted to be part of polysome. Predicted to be active in several cellular components, including dendrite; growth cone; and postsynaptic density. Is expressed in mesoderm; musculature system; and somite. Orthologous to human FXR2 (FMR1 autosomal homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56215 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004087 | K Homology domain |
| Domain | IPR004088 | K Homology domain, type 1 |
| Domain | IPR008395 | Agenet-like domain |
| Domain | IPR022034 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core |
| Domain | IPR032172 | Fragile X-related protein 1, C-terminal region 1 |
| Domain | IPR040472 | Synaptic functional regulator FMRP, KH0 domain |
| Domain | IPR041560 | FMR1, tudor domain |
| Domain | IPR047420 | RNA-binding protein FXR2, second Tudor-like Agenet domain |
| Domain | IPR047421 | RNA-binding protein FXR2, first Tudor-like Agenet domain |
| Domain | IPR047422 | RNA-binding protein FXR2, first type I K homology domain |
| Domain | IPR047424 | RNA-binding protein FXR2, second type I K homology domain |
| Family | IPR040148 | Fragile X messenger ribonucleoprotein 1 |
| Homologous_superfamily | IPR036612 | K Homology domain, type 1 superfamily |
Domain Details Per Protein
| Protein | Length | Agenet-like domain | FMR1, tudor domain | Fragile X messenger ribonucleoprotein 1 | Fragile X messenger ribonucleoprotein 1-like, C-terminal core | Fragile X-related protein 1, C-terminal region 1 | K Homology domain | K Homology domain, type 1 | K Homology domain, type 1 superfamily | RNA-binding protein FXR2, first Tudor-like Agenet domain | RNA-binding protein FXR2, first type I K homology domain | RNA-binding protein FXR2, second Tudor-like Agenet domain | RNA-binding protein FXR2, second type I K homology domain | Synaptic functional regulator FMRP, KH0 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NY99
|
676 |
Interactions and Pathways
No data available
Plasmids
No data available