Gene
wdr45b
- ID
- ZDB-GENE-040426-863
- Name
- WD repeat domain 45B
- Symbol
- wdr45b Nomenclature History
- Previous Names
-
- wdr45l
- zgc:56002 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have phosphatidylinositol-3,5-bisphosphate binding activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including autophagy of mitochondrion; autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to localize to several cellular components, including extrinsic component of membrane; lysosome; and phagophore assembly site membrane. Orthologous to human WDR45B (WD repeat domain 45B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56002 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures | 617977 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PROPPIN | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZUW6
|
344 | ||||
|
UniProtKB:A8KC31
|
344 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wdr45b-201
(1)
|
Ensembl | 2,074 nt |
Interactions and Pathways
No data available
Plasmids
No data available