Gene
rnf8
- ID
- ZDB-GENE-040426-849
- Name
- ring finger protein 8, E3 ubiquitin protein ligase
- Symbol
- rnf8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have several functions, including protein homodimerization activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in several processes, including DNA metabolic process; protein ubiquitination; and regulation of nucleobase-containing compound metabolic process. Predicted to localize to several cellular components, including chromosome; cytosol; and ubiquitin ligase complex. Orthologous to human RNF8 (ring finger protein 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55936 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017907 | Zinc finger, RING-type, conserved site |
| Domain | IPR000253 | Forkhead-associated (FHA) domain |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR018957 | Zinc finger, C3HC4 RING-type |
| Family | IPR017335 | E3 ubiquitin-protein ligase RNF8 |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Length | E3 ubiquitin-protein ligase RNF8 | Forkhead-associated (FHA) domain | SMAD/FHA domain superfamily | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q803C1
|
485 |
Interactions and Pathways
No data available
Plasmids
No data available