Gene
brpf1
- ID
- ZDB-GENE-040426-731
- Name
- bromodomain and PHD finger containing, 1
- Symbol
- brpf1 Nomenclature History
- Previous Names
-
- zgc:55530 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits histone binding activity. Involved in anterior/posterior pattern specification. Localizes to nuclear chromatin. Is expressed in brain; digestive system; epithelium; head; and olfactory pit. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55530 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Laue et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with dysmorphic facies and ptosis | 617333 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Domain | IPR019542 | Enhancer of polycomb-like, N-terminal |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR034732 | Extended PHD (ePHD) domain |
| Domain | IPR042008 | BRPF1, PHD domain |
| Domain | IPR042061 | Peregrin, ePHD domain |
| Family | IPR050701 | Histone Modification Regulator |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | BRPF1, PHD domain | Enhancer of polycomb-like, N-terminal | Extended PHD (ePHD) domain | Histone Modification Regulator | Peregrin, ePHD domain | Zinc finger C2H2-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2L9X9
|
1259 | ||||||||||||||
|
UniProtKB:H9GXF8
|
1248 | ||||||||||||||
|
UniProtKB:Q803M2
|
899 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available