Gene

nck2a

ID
ZDB-GENE-040426-686
Name
NCK adaptor protein 2a
Symbol
nck2a Nomenclature History
Previous Names
  • zgc:55283 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have SH3/SH2 adaptor activity. Predicted to be involved in regulation of translation. Predicted to localize to endoplasmic reticulum. Is expressed in rhombomere 3 and rhombomere 5. Orthologous to human NCK2 (NCK adaptor protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Choe et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nck2a Human Ortholog
No data available
Associated With nck2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Domain IPR035559 Nck2, SH3 domain 1
Domain IPR035561 Nck2, SH3 domain 3
Domain IPR035883 Nck2, SH2 domain
Family IPR017304 Cytoplasmic protein NCK
Family IPR051184 Tyrosine-phosphorylated adapter molecule
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Cytoplasmic protein NCK Nck2, SH2 domain Nck2, SH3 domain 1 Nck2, SH3 domain 3 SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily Tyrosine-phosphorylated adapter molecule
UniProtKB:A0A8M9Q4I8 403
UniProtKB:Q803A2 403
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nck2a-201 (1) Ensembl 4,797 nt
mRNA nck2a-203 (1) Ensembl 243 nt
ncRNA nck2a-002 (1) Ensembl 971 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations