Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2848
Gene Name: hexokinase 1
Gene Symbol: hk1
Previous Names: DrHXK1 (1), im:7148527, wu:fc09d08, wu:fc16e02, wu:fc21e02, wu:fq14b11, zgc:55790 (1), zgc:77618
Nomenclature History
GENE EXPRESSION
All Expression Data: 17 figures from 3 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2004 [IMAGE:7148527]
  4 figures (13 images) from Rauch et al., 2003 [fq14b11]
  6 figures (18 images) from Thisse et al., 2004 [MGC:77618]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  adaxial cell, basal plate midbrain region, brain, central nervous system (all 29) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la018460Tg, sa18424
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Hemolytic anemia due to hexokinase deficiency 235700
Neuropathy, hereditary motor and sensory, Russe type 605285
GENE ONTOLOGY
Ontology GO Term
Biological Process carbohydrate metabolic process (more)
Cellular Component cytosol (more)
Molecular Function ATP binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001312 (1)
  • InterPro:IPR019807 (1)
  • InterPro:IPR022672 (1)
  • InterPro:IPR022673 (1)
  • PROSITE:PS00378 (1)
  • Pfam:PF00349 (1)
  • Pfam:PF03727 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hk1-001 (1) 4061
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hk1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    hk1 Contained in: [BAC] CH211-1N9 (1) (order this), DKEY-226B20 (1)
    hk1 Encodes: [EST] fc09d08 (1), fc16e02 (1), fc21e02 (1), fq14b11 (1), IMAGE:7148527 (1) (order this)
    [cDNA] MGC:55790 (1) (order this), MGC:77618 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213252 (1) 4079 bp
    Genomic GenBank:BX546482 (1) 206949 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NX09 (1) 918 aa
    Sequence Clusters UniGene:9278 (1)
    Sequence Information (all 21)
    OTHER hk1 GENE PAGES
  • Gene:406791 (1)
  • VEGA:OTTDARG00000022817 (1)
  • Ensembl(Zv9):ENSDARG00000039452 (1)
  • MAPPING INFORMATION
    Chr: 13 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish hk1 13  
    Human HK1 10 (10q22)
  • OMIM:142600
  • Gene:3098
  • Mouse Hk1 10 ( 32.37 cM)
  • MGI:96103
  • Gene:15275
  • CITATIONS (21)