Gene

cnot8

ID

ZDB-GENE-040426-2845

Name

CCR4-NOT transcription complex, subunit 8

Symbol

cnot8 Nomenclature History

Previous Names

wu:fe49a05
zgc:63844 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have poly(A)-specific ribonuclease activity. Involved in neuron development. Predicted to localize to CCR4-NOT core complex and P-body. Orthologous to human CNOT8 (CCR4-NOT transcription complex subunit 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6908033 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Koch et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cnot8 Human Ortholog

No data available

Associated With cnot8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR006941	Ribonuclease CAF1
Family	IPR039637	CCR4-NOT transcription complex subunit 7/8/Pop2
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily