Gene
fpgs
- ID
- ZDB-GENE-040426-2781
- Name
- folylpolyglutamate synthase
- Symbol
- fpgs Nomenclature History
- Previous Names
-
- fk51d09
- wu:fk49h03
- wu:fk51d09
- zgc:63807
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in tetrahydrofolylpolyglutamate biosynthetic process. Predicted to localize to cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; liver; nervous system; optic vesicle; and yolk syncytial layer. Orthologous to human FPGS (folylpolyglutamate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63807 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018109 | Folylpolyglutamate synthetase, conserved site |
| Family | IPR001645 | Folylpolyglutamate synthetase |
| Family | IPR023600 | Folylpolyglutamate synthase, eukaryota |
| Homologous_superfamily | IPR036565 | Mur-like, catalytic domain superfamily |
| Homologous_superfamily | IPR036615 | Mur ligase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Folylpolyglutamate synthase, eukaryota | Folylpolyglutamate synthetase | Folylpolyglutamate synthetase, conserved site | Mur ligase, C-terminal domain superfamily | Mur-like, catalytic domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:F1Q7N0
|
572 |
Interactions and Pathways
No data available
Plasmids
No data available