Gene
rhoac
- ID
- ZDB-GENE-040426-2665
- Name
- ras homolog gene family, member Ac
- Symbol
- rhoac Nomenclature History
- Previous Names
-
- wu:fc17g01
- zgc:63939
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in skeletal muscle satellite cell migration; stress fiber assembly; and wound healing, spreading of cells. Predicted to act upstream of or within small GTPase mediated signal transduction. Predicted to be located in plasma membrane. Predicted to be active in cleavage furrow; cytoplasm; and dendritic spine. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63939 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies, somatic mosaic | 618727 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase Rho | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q7T2E8
|
193 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available