Gene
pccb
- ID
- ZDB-GENE-040426-2467
- Name
- propionyl-CoA carboxylase subunit beta
- Symbol
- pccb Nomenclature History
- Previous Names
-
- zgc:85813
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have ligase activity. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Is expressed in several structures, including alar plate midbrain region; musculature system; optic tectum; optic vesicle; and pronephros. Orthologous to human PCCB (propionyl-CoA carboxylase subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6893522 (1 image)
- IMAGE:7148931 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| propionic acidemia | Alliance | Propionicacidemia | 606054 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011762 | Acetyl-coenzyme A carboxyltransferase, N-terminal |
| Domain | IPR011763 | Acetyl-coenzyme A carboxyltransferase, C-terminal |
| Domain | IPR034733 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta |
| Homologous_superfamily | IPR029045 | ClpP/crotonase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | Acetyl-coenzyme A carboxyltransferase, C-terminal | Acetyl-coenzyme A carboxyltransferase, N-terminal | ClpP/crotonase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6NWC8
|
557 | ||||
|
UniProtKB:B0V0X1
|
555 |
Interactions and Pathways
No data available
Plasmids
No data available