Gene

eif5a2

ID

ZDB-GENE-040426-2405

Name

eukaryotic translation initiation factor 5A2

Symbol

eif5a2 Nomenclature History

Previous Names

wu:fb05b06
wu:fc23f04
wu:fc61c10
zgc:55504 (1)
zgc:77429

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translational initiation. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human EIF5A2 (eukaryotic translation initiation factor 5A2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55504 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif5a2 Human Ortholog

No data available

Associated With eif5a2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR020189	Translation elongation factor, IF5A C-terminal
Domain	IPR048670	Translation initiation factor 5A-like, N-terminal
Family	IPR001884	Translation elongation factor IF5A-like
Homologous_superfamily	IPR008991	Translation protein SH3-like domain superfamily
Homologous_superfamily	IPR012340	Nucleic acid-binding, OB-fold
Homologous_superfamily	IPR014722	Large ribosomal subunit protein uL2, domain 2
PTM	IPR019769	Translation elongation factor, IF5A, hypusine site

Domain Details Per Protein

Protein	Length	Large ribosomal subunit protein uL2, domain 2	Nucleic acid-binding, OB-fold	Translation elongation factor, IF5A C-terminal	Translation elongation factor, IF5A, hypusine site	Translation elongation factor IF5A-like	Translation initiation factor 5A-like, N-terminal	Translation protein SH3-like domain superfamily
UniProtKB:Q7ZUP4 InterPro	155

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eif5a2-201 (1) Ensembl	Ensembl	2,793 nt	Select Tool ZFIN BLAST
mRNA	eif5a2-202 (1) Ensembl	Ensembl	471 nt	Select Tool ZFIN BLAST
mRNA	eif5a2-203 (1) Ensembl	Ensembl	814 nt	Select Tool ZFIN BLAST
mRNA	eif5a2-204 (1) Ensembl	Ensembl	626 nt	Select Tool ZFIN BLAST
mRNA	eif5a2-205 (1) Ensembl	Ensembl	830 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations