Gene
trnau1apb
- ID
- ZDB-GENE-040426-2386
- Name
- tRNA selenocysteine 1 associated protein 1b
- Symbol
- trnau1apb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Orthologous to human TRNAU1AP (tRNA selenocysteine 1 associated protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6897971 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa13677 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR034510 | SECp43, RNA recognition motif 2 |
| Domain | IPR041085 | tRNA selenocysteine 1-associated protein 1, C-terminal |
| Family | IPR040434 | tRNA selenocysteine 1-associated protein 1 |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
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Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | SECp43, RNA recognition motif 2 | tRNA selenocysteine 1-associated protein 1 | tRNA selenocysteine 1-associated protein 1, C-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q4KM14
|
316 | ||||||
|
UniProtKB:F1QXG2
|
316 | ||||||
|
UniProtKB:A0A8M9Q082
|
218 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trnau1apb-201
(1)
|
Ensembl | 1,723 nt | ||
| ncRNA |
trnau1apb-002
(1)
|
Ensembl | 2,410 nt | ||
| ncRNA |
trnau1apb-003
(1)
|
Ensembl | 755 nt | ||
| ncRNA |
trnau1apb-004
(1)
|
Ensembl | 802 nt | ||
| ncRNA |
trnau1apb-005
(1)
|
Ensembl | 692 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-77A20 | ZFIN Curated Data | |
| Encodes | EST | fa56b07 | ||
| Encodes | EST | fc12c07 | ||
| Encodes | EST | fc69f09 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:6897971 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:77884 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:113964 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_213251 (1) | 2232 nt | ||
| Genomic | GenBank:BX000358 (1) | 181081 nt | ||
| Polypeptide | UniProtKB:F1QXG2 (1) | 316 aa |
- Li, X., Liu, H., Li, D., Lei, H., Wei, X., Schlenk, D., Mu, J., Chen, H., Yan, B., Xie, L. (2021) Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish (Danio rerio). Environmental science & technology. 55:11894-11905
- Betancor, M.B., Almaida-Pagán, P.F., Sprague, M., Hernández, A., Tocher, D.R. (2015) Roles of selenoprotein antioxidant protection in zebrafish, Danio rerio, subjected to dietary oxidative stress. Fish physiology and biochemistry. 41(3):705-20
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Penglase, S., Hamre, K., Ellingsen, S. (2014) Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury. Free radical biology & medicine. 75:95-104
- Benner, M.J., Settles, M.L., Murdoch, G.K., Hardy, R.W., and Robison, B.D. (2013) Sex specific transcriptional responses of the zebrafish (Danio rerio) brain selenoproteome to acute sodium selenite supplementation. Physiological Genomics. 45(15):653-66
- Benner, M.J., Drew, R.E., Hardy, R.W., and Robison, B.D. (2010) Zebrafish (Danio rerio) vary by strain and sex in their behavioral and transcriptional responses to selenium supplementation. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 157(4):310-318
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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