Gene
ednrab
- ID
- ZDB-GENE-040426-2364
- Name
- endothelin receptor type Ab
- Symbol
- ednrab Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have endothelin receptor activity. Involved in cardioblast migration to the midline involved in heart rudiment formation; cartilage development; and embryonic viscerocranium morphogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Is expressed in cranial ganglion; gill; neural crest; and pharyngeal arch. Orthologous to human EDNRA (endothelin receptor type A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85942 (16 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Endothelin receptor A | Endothelin receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M1P7F8
|
408 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ednrab-201
(1)
|
Havana | 1649 nt |
Interactions and Pathways
No data available
Plasmids
No data available