Gene
rffl
- ID
- ZDB-GENE-040426-2274
- Name
- ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
- Symbol
- rffl Nomenclature History
- Previous Names
-
- zgc:77828
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin protein ligase activity. Predicted to be involved in cellular protein metabolic process and negative regulation of apoptotic process. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001841 | Zinc finger, RING-type |
Domain | IPR049320 | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger |
Domain | IPR049322 | E3 ubiquitin-protein ligase CARP2, FYVE/PHD zinc finger |
Family | IPR051728 | RING-FYVE domain-containing E3 ubiquitin-protein ligase |
Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Homologous_superfamily | IPR036361 | SAP domain superfamily |
Domain Details Per Protein
Protein | Length | E3 ubiquitin-protein ligase CARP1/2, FYVE/PHD zinc finger | E3 ubiquitin-protein ligase CARP2, FYVE/PHD zinc finger | RING-FYVE domain-containing E3 ubiquitin-protein ligase | SAP domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
---|---|---|---|---|---|---|---|---|
UniProtKB:X1WG81
|
325 | |||||||
UniProtKB:Q6NX02
|
346 | |||||||
UniProtKB:A0A8M9QBX2
|
260 | |||||||
UniProtKB:F1QFN6
|
346 |
Interactions and Pathways
No data available
Plasmids
No data available