Gene
tead1a
- ID
- ZDB-GENE-040426-2101
- Name
- TEA domain family member 1a
- Symbol
- tead1a Nomenclature History
- Previous Names
-
- tead1
- zgc:63696
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity; DNA-binding transcription factor activity; and RNA polymerase II transcription factor binding activity. Predicted to be involved in embryonic organ development; hippo signaling; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription factor complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Is expressed in nervous system; neural plate; and somite. Orthologous to human TEAD1 (TEA domain transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63696 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Fillatre et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sveinsson chorioretinal atrophy | Alliance | Sveinsson chorioretinal atrophy | 108985 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | TEA/ATTS domain | TEA/ATTS domain superfamily | TEC1/TEAD Transcription Factor | Transcriptional enhancer factor, metazoa | YAP binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B730
|
422 | |||||
|
UniProtKB:Q7SXX3
|
393 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tead1a-201
(1)
|
Ensembl | 748 nt | ||
| mRNA |
tead1a-202
(1)
|
Ensembl | 1,744 nt | ||
| ncRNA |
tead1a-003
(1)
|
Ensembl | 817 nt |
Interactions and Pathways
No data available
Plasmids
No data available