Gene
pak5
- ID
- ZDB-GENE-040426-2085
- Name
- p21 protein (Cdc42/Rac)-activated kinase 5
- Symbol
- pak5 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; cytoskeleton organization; and protein phosphorylation. Is expressed in central nervous system and spinal cord. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76890 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR028754 | Serine/threonine-protein kinase PAK5, catalytic domain |
| Domain | IPR033923 | p21 activated kinase binding domain |
| Family | IPR050285 | STE20 Serine/Threonine-Protein Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036936 | CRIB domain superfamily |
Domain Details Per Protein
| Protein | Length | CRIB domain | CRIB domain superfamily | p21 activated kinase binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase PAK5, catalytic domain | STE20 Serine/Threonine-Protein Kinase |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NVJ4
|
711 |
Interactions and Pathways
No data available
Plasmids
No data available