Gene
srsf1a
- ID
- ZDB-GENE-040426-1950
- Name
- serine and arginine rich splicing factor 1a
- Symbol
- srsf1a Nomenclature History
- Previous Names
-
- sfrs1a
- sfrs1l (1)
- wu:fb52g10
- wu:fb97g12
- zgc:66146
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to nuclear speck. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66146 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities | Alliance | Neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities | 620489 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR029538 | Serine/arginine-rich splicing factor 1, RNA recognition motif 2 |
| Domain | IPR034520 | SRSF1, RNA recognition motif 1 |
| Family | IPR050374 | RRT5/SRSF/Splicing Factor SR |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | RRT5/SRSF/Splicing Factor SR | Serine/arginine-rich splicing factor 1, RNA recognition motif 2 | SRSF1, RNA recognition motif 1 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SXP4
|
257 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
srsf1a-201
(1)
|
Ensembl | 2,171 nt | ||
| mRNA |
srsf1a-202
(1)
|
Ensembl | 770 nt | ||
| mRNA |
srsf1a-203
(1)
|
Ensembl | 543 nt | ||
| ncRNA |
srsf1a-003
(1)
|
Ensembl | 643 nt |
Interactions and Pathways
No data available
Plasmids
No data available