Gene

naprt

ID

ZDB-GENE-040426-1897

Name

nicotinate phosphoribosyltransferase

Symbol

naprt Nomenclature History

Previous Names

naprt1
zgc:77870

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable nicotinate phosphoribosyltransferase activity. Predicted to be involved in NAD biosynthetic process via the salvage pathway and response to oxidative stress. Predicted to act upstream of or within pyridine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; polster; and pronephric duct. Orthologous to human NAPRT (nicotinate phosphoribosyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77870 (14 images)
IMAGE:7160001 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With naprt Human Ortholog

No data available

Associated With naprt Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040727	Nicotinate phosphoribosyltransferase, N-terminal domain
Domain	IPR041619	Nicotinate phosphoribosyltransferase C-terminal domain
Family	IPR006405	Nicotinate phosphoribosyltransferase pncB-type
Family	IPR007229	Nicotinate phosphoribosyltransferase family
Homologous_superfamily	IPR013785	Aldolase-type TIM barrel
Homologous_superfamily	IPR036068	Nicotinate phosphoribosyltransferase-like, C-terminal